In its first open-ended strike in 22 years, Nevada's largest union called on hundreds of workers at Virgin Hotels Las Vegas to walk off the job Friday morning as negations failed.

Hundreds of Las Vegas hotel workers have gone on strike at a casino near the Strip. It's the first open-ended strike in 22 years for the Culinary Workers Union, which represents 60,000 hospitality workers across Nevada.

LAS VEGAS, Nev. (FOX5) - For the second time this year, Culinary Union workers are on strike at Virgin Hotels. The strike began Friday at 5 a.m. after the latest round of negotiations failed, leaving the union and off-strip property “disappointed.”