The latest was a 36-24 defeat in Week 6. The Seahawks got to within five points late in the fourth quarter before San Francisco pulled away, but they also benefitted from a missed call on what should have been a muffed punt that would have given the 49ers possession deep in Seattle territory.

Preview the Week 11 matchup between the San Francisco 49ers and Seattle Seahawks with predictions, odds, over/under, spread, betting lines and more.

The game at Tampa Bay was a virtual must-win for the previously 4-4 49ers. A loss to fall to 4-5 could have been catastrophic. Alas, they pulled out a 23-20 victory on the road. While it was a significant win, it was only Step 1 for the 49ers. Perhaps more important is Sunday’s matchup against the Seattle Seahawks.