Left tackle Trent Williams’ ankle and wrist injuries could force him to miss his first 49ers game this season Sunday against ...

San Francisco head coach Kyle Shanahan discussed Friday the 49ers' offensive line ahead of a matchup with the Seattle ...

The 49ers definitely will be without defensive tackle Kevin Givens (groin), punter Mitch Wishnowsky (back) and cornerback ...

Matt Lively reports on three things that will help the San Francisco 49ers seal a sweep over the Seattle Seahawks on Sunday.

Metcalf hasn’t played since he sprained his knee Oct. 20. Lucas will be making his season debut. Connor Williams is out at ...

The San Francisco 49ers need a win in Week 11 over the Seattle Seahawks. Their injury situation may make it a significant ...

The quarterback is winless in five starts against the 49ers and Seahawks have lost six consecutive games to the 49ers in the ...

Even with McCaffrey, the NFL’s rushing leader in 2023, missing the first eight games, the 49ers are ranked No. 6 in rushing ...

The Seahawks have ruled out three players for Sunday's game against the 49ers, including a key part of the offensive line.

Don’t expect the San Francisco 49ers to take their foot off the gas in their usage of running back Christian McCaffrey.

What to look for from the top 49ers and Seahawks players and how to watch the game as they face off on Sunday, week 11.

Christian McCaffrey had 107 yards from scrimmage in his season debut. The 49ers are a different team when McCaffrey is on the ...