SANTA CLARA, Calif. — The season debut of Christian McCaffrey helped make the San Francisco 49ers’ offence look more like it did a year ago than it did in an up-and-down first half of the season.

The Seahawks return from the bye week and get set to take on the division rival San Francisco 49ers in their final head-to-head matchup of the regular season. Seahawks reporter Jen Mueller breaks down ...

The San Francisco 49ers D/ST unit will look to give the division-rival Seattle Seahawks a rude welcome to Santa Clara on Sunday. The 49ers are the sixth-most productive unit among fantasy D/STs.

The 49ers Pride Capsule Collection represents the LGBTQ+ community that is woven through the fabric of the 49ers Faithful. An ...

Look back on the Ravens' win against the Bengals with Arthur Maulet mic'd and ahead to Baltimore's big game against the Steelers.

The Seahawks have not beat the 49ers since Geno Smith took over at QB. But Smith insisted his confidence hasn't wavered, despite Seattle's recent struggles.

The Seattle Seahawks will have to deal with Christian McCaffrey after the star running back returned from injury last week.

Christian McCaffrey called out so-called Instagrm doctors for trying to diagnose his Achilles injury before his return.

SportsLine's Model reveals its top Week 11 NFL picks, NFL best bets, NFL parlay picks, NFL parlay card, NFL predictions, and ...

Get ready for the Lions' Week 11 matchup against the Jacksonville Jaguars, with this game trailer, presented by Frankenmuth ...

How will the second half of the season go for the Green Bay Packers now that they've had their bye week? We predict every remaining game.

SportsLine's model simulated Seattle Seahawks vs. San Francisco 49ers 10,000 times and made its Week 11 NFL picks, ...