SportsLine's model simulated Seattle Seahawks vs. San Francisco 49ers 10,000 times and made its Week 11 NFL picks, ...

Seattle Seahawks coach Mike Macdonald faced an unusual conundrum this week as he game-planned for Sunday's rematch with the ...

Left tackle Trent Williams’ ankle and wrist injuries could force him to miss his first 49ers game this season Sunday against ...

San Francisco head coach Kyle Shanahan discussed Friday the 49ers' offensive line ahead of a matchup with the Seattle ...

Preview the Week 11 matchup between the San Francisco 49ers and Seattle Seahawks with predictions, odds, over/under, spread, ...

The San Francisco 49ers need a win in Week 11 over the Seattle Seahawks. Their injury situation may make it a significant ...

The quarterback is winless in five starts against the 49ers and Seahawks have lost six consecutive games to the 49ers in the ...

The 49ers definitely will be without defensive tackle Kevin Givens (groin), punter Mitch Wishnowsky (back) and cornerback ...

Two 49ers stars are questionable for San Francisco's NFC West showdown against the Seattle Seahawks on Sunday at Levi's ...

Even with McCaffrey, the NFL’s rushing leader in 2023, missing the first eight games, the 49ers are ranked No. 6 in rushing ...

The Seahawks have ruled out three players for Sunday's game against the 49ers, including a key part of the offensive line.

Matt Lively reports on three things that will help the San Francisco 49ers seal a sweep over the Seattle Seahawks on Sunday.