The federal government has proven that it can navigate the difficult process of identifying drugs for price negotiation, gathering and analyzing key information, and negotiating with manufacturers.

IgG4-related disease is a multiorgan, relapsing, fibroinflammatory, immune-mediated disorder with no approved therapy. Inebilizumab targets and depletes CD19+ B cells and may be effective for ...

In Western countries, perioperative chemotherapy is the standard of care for resectable gastric cancer. Interest has been high in adding preoperative chemoradiotherapy to this treatment.

Lung transplantation has evolved over 60 years from an experimental to an accepted standard treatment for life-threatening lung disease. Suitable recipients can expect improved survival and ...

Obesity is chronic disease and causal precursor to myriad other conditions, including type 2 diabetes. In an earlier analysis of the SURMOUNT-1 trial, tirzepatide was shown to provide substantial ...

A 44-year-old woman presented to the primary care clinic with a 2-year history of shortness of breath with minimal exertion, cough productive of clear sputum, generalized fatigue, and an ...

Dr. Yanki Okuducu (Pediatrics): A newborn girl was admitted to the neonatal intensive care unit (NICU) of this hospital because of cardiorespiratory arrest at delivery. The newborn’s mother was ...

Important adverse events included infusion-related and hypersensitivity reactions in 25 of 306 immunocompromised participants (8.2%) who received pemivibart and anaphylaxis in 4 of 623 ...

The JN.1 subvariant of SARS-CoV-2 emerged in late 2023 and rapidly became dominant globally. In the past 6 months, JN.1 has continued to evolve, giving rise to multiple sublineages with unique ...

The NHS in England has historically delivered high quality at low cost, but recently, its performance has declined. The challenges facing the NHS hold potential lessons for the United States.

Read before the Philadelphia County Medical Society, October 17, 1883. Physician to the Philadelphia Hospital for Skin Diseases, Lecturer and Instructor on Diseases of the Skin in the Summer ...

How neoadjuvant immunotherapy compares with standard adjuvant immunotherapy in patients with resectable, macroscopic stage III melanoma has been unclear. New research findings are summarized in a ...